Protein Purification
Abcam Ebselen, mimic of glutathione pero x idase, 5MG
MW 274.19 Da, Purity >98%. Seleno-organic compound, antioxidant, mimic of glutathione peroxidase. Inhibitor of lipoxygenases, NO synthases, NADPH oxidase, protein kinase C and H+/K(+)-ATPase producing anti-inflammatory effects.
The product is subject to the following: Abcam Restricted Use Statement
Echelon Biosciences Research Labs PI(4)P GRIP 2.5 ug
Each vial of PI(4)P Grip contains lyophilized, recombinant N-terminal GST-tagged Legionella pneumophila SidC protein, C-terminal fragment. This PI(4)P-specific binding protein can be used as a control reagent with PIP Strips and PIP Arrays. It is easily reconstituted in water or buffered solutions. Each 2.5 g vial contains enough protein for use on one PIP Strip or PIP Array. SidC-3C prefers binding PI(4)P when it is in a membrane-like environment (liposome, PIP Strip, etc.) and does not bind PI(4)P in solution (e.g. short chain lipids such as diC4 and diC8 PI(4)P. PI(4)P Grip can be detected with commercial anti-GST antibodies. This item is non returnable
AdipoGen ANGPTL3 FLD h rec
Recombinant Protein. Fibrinogen-like domain of human ANGPTL3 aa 224-460 is fused at the N-terminus to a FLAG -tag. Source/Host HEK 293 cells. Endotoxin <0.01EU/µg purified protein LAL test. Lyophilized. Contains PBS. ANGPTL3 Angiopoietin-like protein 3 regulates angiogenesis and also directly regulates lipid, glucose and energy metabolism. Angiopoietin-like 3 ANGPTL3 is a regulator of plasma triglyceride TRG levels due to its inhibitory action on the activity of lipoprotein lipase LPL. ANGPTL3 induces angiogenesis by binding to integrin alphavbeta3. ANGPTL3 is predominantly produced in the liver and can therefore be classified as a hepatokine. In the human plasma, ANGPTL3 is cleaved to released two fragments a N-terminal coiled-coil domain-containing fragment aa17-207 important for inhibiting the lipolysis of triglyceride and the C-terminal fibrinogen-like domain-containing fragment aa208-460.
Cayman Chemical GST GlutathIon 1ea
An NQO1 substrate and a derivative ofBlapachone converted by NQO1 to NAD and increases the ratio of NAD to NADH in a cell-free assay as well as C2C12 and L6 myoblasts at 1 1 or 2 UM respectively increases intracellular ATP levels as well as decreases intracellular lactate and ROS levels in primary fibroblasts isolated from patients with MELAS at 1 UM increases the levels of mitochondrial complex I and mitochondrial complex III as well as increases the OCR in primary fibroblasts isolated from patients with MELAS at 1 UM inhibits cisplatin-induced apoptosis production of mitochondrial ROS and mitochondrial membrane depolarization in primary mouse cochlear organ of Corti cells at 1 UM
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ABclonal Technology [KO Validated] Glutathione Synthetase (GSS) Rabbit pAb
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
Cayman Chemical S-Acetyl-L-glutathIon 10g
A derivative of glutathione; more stable in plasma than GSH; converted to GSH by intracellular thioesterases; increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency at 50 μM; induces apoptosis in Daudi, Raji, and Jurkat lymphoma cells at 5 mM; inhibits the replication of HSV-1 in human foreskin fibroblasts at 5 and 10 mM; increases survival in a mouse model of HSV-1 infection at 6.25 μg/g per day
Cayman Chemical GlutathIon CelBased Detect 96
Glutathione (GSH) is a low molecular-weight tripeptide thiol that serves as a primary cellular anti-oxidant and plays a fundamental role in the elimination of environmental toxins. During EArly apoptosis, cells may exclude GSH, causing a decrease in intracellular GSH levels. The intracellular level of GSH is thus used as an indicator of cell health. Cayman’s Cell-Based Glutathione Assay Kit (Blue Fluorescence) employs a cell-permeable dye, monochlorobimane (MCB), which reacts with GSH to generate a highly fluorescent product that can be measured using excitation and emission wavelengths of 380 and 480 nm, respectively. The kit can be EAsily adapted to screening programs for therapeutic compounds regulating intracellular GSH levels.
AdipoGen TNFalpha msmultimericrec
Protein. The extracellular domain of mouse TNF-alpha aa 77-235 is fused at the N-terminus to mouse ACRP30headless aa 18-111 and a FLAG -tag. Source HEK 293 cells. Endotoxin content <0.02EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. Binds to human and mouse TNF-R1 and TNF-R2. Purity >95% SDS-PAGE. Tumor necrosis factor TNF, cachexin or cachectin and formerly known as tumor necrosis factor-alpha is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. MultimericTNF-alpha™ is a high activity construct in which two trimeric TNF-alpha ligands are artificially linked via the collagen domain of ACRP30. The receptor TNF-R1 is activated by both the membrane-bound and soluble trimeric forms of TNF-alpha, whereas the receptor TNF-R2 only responds to the membrane-bound form of TNF-alpha TNF-alpha mouse multimeric rec. Prod. No. AG-40B-0021.
Gold Biotechnology Inc Glutathione Agarose Resin 5 mL
Glutathione has been covalently linked for use in affinity purification of glutathione-S-transferase (GST) and GST fusion proteins.
ABclonal Technology Glutathione Peroxidase 2
The protein encoded by this gene is a member of the glutathione peroxidase family which reduces organic hydroperoxides and hydrogen peroxide (H2O2) using glutathione to protect against oxidative damage This isozyme is primarily expressed in the gastrointestinal tract and liver localized in the cytoplasm and prefers hydrogen peroxide as a substrate Overexpression is linked to increased differentiation and proliferation in colorectal cancer As a selenoprotein it contains selenocysteine (Sec) at its active site encoded by the UGA codon The 3 UTR of selenoprotein mRNAs has a Sec insertion sequence (SECIS) element enabling UGA to code for Sec instead of terminating translation Alternative splicing results in different transcript variants
AdipoGen IL-37 aa 46-218hrecHis
Protein. Human IL-37 aa Val46-Asp218 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <0.1EU/µg purified protein LAL test Lonza. Lyophilized from 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >95% SDS-PAGE. IL-37 IL-1F7 IL-1H4 is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells PBMCs and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor IL-18R and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide LPS-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.
Carnabio Usa Inc COT(MAP3K8)/10UG/CATALYTIC
COT(MAP3K8), Catalytic domain, Wild type, Amino Acid 30-397, NP_005195.2, Expressed in Insect (sf21); 10microg
Cambridge Isotope Laboratories GLUTATHIONE DISULFIDE GSS 5MG
Glutathione disulfide (GSSG) (glycines-¹³C₂,98%;¹⁵N,96-99%) 65-70% net peptide /peptide purity 90%
AdipoGen 3-HKT Anopheles guntagged
Protein. Full-length 3-HKT Anopheles gambiae is untagged. Source E. coli. Endotoxin content N/A. Liquid. In 20mM TRIS-HCl pH 8.0, containing 150mM NaCl and 40µM pyridoxal 5-phosphate PLP. Purity >99% SDS-PAGE. The 3-hydroxykynurenine transaminase 3-HKT gene plays a vital role in the development of malaria parasites by participating in the synthesis of xanthurenic acid, which is involved in the exflagellation of microgametocytes in the midgut of malaria vector species. The 3-HKT enzyme is involved in the tryptophan metabolism of Anophelines. The gene had been studied in the important global malaria vector, Anopheles gambiae.
Cayman Chemical S-NItroso-L-glutathIon 10mg
S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition, and metal content.{1277,5064,4274,3632}